Diffusion tensor magnetic resonance imaging driven growth modeling for radiotherapy target definition in glioblastoma
نویسندگان
چکیده
منابع مشابه
Glioblastoma growth modeling for radiotherapy target delineation
Radiotherapy treatment planning requires a localization of the tumor within the patient. This is challenging to accomplish for microscopic infiltrative spread of disease that is not visible on current imaging modalities. Prime examples for infiltrative tumors are gliomas. With the help of mathematical models, common growth characteristics of gliomas, which are known from histopathological studi...
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Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they are able to detect tumor volume and physiological changes beyond the lesions shown on conventional MRI. This review examines recent studies that utilized diffusion and perfusion MRI for tumor volume...
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In radiotherapy of gliomas, a precise definition of the treatment volume is problematic, because current imaging modalities reveal only the central part of the tumor with a high cellular density, but fail to detect all regions of microscopic tumor cell spread in the adjacent brain parenchyma. Mathematical models can be used to integrate known growth characteristics of gliomas into the target de...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 2017
ISSN: 0284-186X,1651-226X
DOI: 10.1080/0284186x.2017.1374559